Importantly, it does not have cross-resistance with current artemisinin-based combination therapy so the use of chloroquine would not compromise the efficacy of first-line treatment.

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if no chloroquine resistance is reported in the area of your travel, the centers for disease control and prevention cdc recommend chloroquine 500mg once weekly beginning 1 week before travel to a malarious area, weekly while in a malarious area, and for 4 weeks after leaving a malarious area.

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