In a relatively large study of 240 children with streptococcal or staphylococcal skin infections, clindamycin was found to be equivalent to erythromycin and slightly superior to penicillin, with no evident adverse effects.

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estradiol moderate anti-infectives that disrupt the normal gi flora, clindamycin, lincomycin, may potentially decrease the effectiveness of estrogen-containing oral contraceptives.

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biologically inactive clindamycin phosphate is rapidly converted to active clindamycin.


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