In some embodiments, the serpina-1 polypeptide comprises the amino acid sequence set forth as mffiqntksplfmgkvvnptqk seq id no 1 .

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for example, such assays may comprise, as the adsorbent, binding moiety, or capture reagent, an antibody to one or more of the biomarkers such as serpina-1 polypeptides and or albumin polypeptides.

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maintenance of annexin a1 at the membrane along with increased membrane levels of the dgc proteins could fully explain the profile of reduced ebd uptake, reduced serum ck levels, and reduced membrane injury with laser stimulation, all of which we observed when serpina3n was overexpressed in the mdx or sgcd backgrounds.

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